PLUS Study

Join us for our 90th episode of the eCritCare podcast, where Jose Chacko & I discuss the recently published landmark trial PLUS. This trial demonstrated no significant difference in 90-day mortality between the saline group and the plasmalyte-148 group.

It raises the question – Does the choice of IV fluid in ICU really matter?

Should we stop worrying about the choice of fluid and focus on not giving so-called “maintenance fluids” to critically ill patients?

The key message is “anything in excess is bad, don’t give something that patient doesn’t need.”