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play_arrow Double Sequential External Defibrillation – A game-changer Dr Swapnil Pawar   Alternate defibrillation strategies for refractory ventricular fibrillation Cheskes S, Verbeek PR, Drennan IR, et al.  N Engl J Med. 2022 Nov 24;387(21):1947-1956. doi: 10.1056/NEJMoa2207304. Epub 2022 Nov 6. PMID: 36342151.   Blog Written by Dr Jose Chacko Background […]

play_arrow TEAM Trial – Early Mobilisation in Intensive Care Dr Swapnil Pawar   Early Active Mobilization during Mechanical Ventilation in the ICU The TEAM Study Investigators and the ANZICS Clinical Trials Group Blog Written by – Dr Jose Chacko  Population and setting The study was held from February 27, 2018, […]

The CLASSIC trial  Blog written by Dr Jose Chacko  Setting and design The CLASSIC trial was a multicentric randomized clinical trial carried out in 31 ICUs in Denmark, Norway, Sweden, Switzerland, Italy, the Czech Republic, the United Kingdom, and Belgium. The study was conducted over a 3-year period between November […]

play_arrow MICHELLE Trial – Rivaroxaban in COVID-19 Dr Swapnil Pawar Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after hospitalisation for COVID-19 (MICHELLE): an open-label, multicentre, randomised, controlled trial Blog Written by – Dr Jose Chacko Question: In patients hospitalized with COVID-19, does prophylaxis with rivaroxaban 10 mg/day for 35 days […]

play_arrow Balanced Salt vs Normal Salt in ICU – Just stick to BASICs Dr Swapnil Pawar Balanced Salt vs Normal Salt in ICU – Just stick to BASICs Blog Written by – Dr Jose Chacko Effect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality […]

play_arrow Neuromuscular Blockade in Intensive Care – To Be or Not To Be Dr Swapnil Pawar   Blog Slides by – Dr Swapnil Pawar Indications for NMB use in ICU – NMB Agents – NMB Monitoring – Evidence – ARDS –   Status Asthmaticus – Raised ICP/Severe TBI – Therapeutic […]

play_arrow Transfusion Thresholds in Intensive Care Dr Swapnil Pawar Transfusion Thresholds in Intensive Care Blog Written by Dr Jose Chacko Incidence of anemia in the ICU Anemia is all too common among critically ill patients, with 30–50% of patients receiving red cell transfusion. The etiology of anemia in the ICU […]

play_arrow Oxygen Therapy in ICU- The Circle of Uncertainty Dr Swapnil Pawar   Background  Clinical practice guidelines give no recommendation for oxygenation targets in adult patients in the ICU owing to sparse evidence. Meta-analysis 2018 Meta-Analysis 2018 ICU-ROX Results LOCO2 Trial HOT- ICU Trial Setting: 35 ICUs in Denmark, Switzerland, […]