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Maddi1

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ICU Primary Prepcast
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Liver Physiology

Dr Maddi Anupindi April 19, 2020

Describe the blood supply to the liver and its regulation The basic functional unit of the liver is the lobule which is composed of a roughly hexagonal arrangement of plates of hepatocytes that radiate around a central vein. The central vein empties into the hepatic vein which then empties into […]

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Renal Physiology

Dr Maddi Anupindi March 22, 2020

Describe normal renal blood flow and its control, including the concept of autoregulation. The kidneys receive approximately 25% of cardiac output or 1250ml/min via the renal arteries. The kidneys have a high oxygen consumption of 18ml/oxygen/minute but a low oxygen extraction of 10%. Therefore, the high renal blood flow is […]

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Obstetric Physiology

Dr Maddi Anupindi February 28, 2020

Outline the cardiovascular, respiratory, haematological and genitourinary changes that occur during pregnancy Cardiovascular: these include effects on cardiac output and mechanical effects Cardiac output Stroke volume:  increases by 20-30%, mainly in the first trimester Heart rate: increases as early as 4 weeks after conception and increases by 17% at the […]