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Opinion


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eCritCare Podcast
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  • 486

Featured

Targeted Temperature Management & Non-shockable Rhythms

Dr Swapnil Pawar October 13, 2019

HYPERION TRIAL Dr Jose Chacko & Dr Swapnil Pawar Targeted temperature management with a target of 32 degrees C to 36 degrees C (moderate therapeutic hypothermia) is currently advocated by ILCOR guidelines for all patients with coma after successful resuscitation from cardiac arrest. TTM Trial results published in 2013, however, showed inconclusive effects of this treatment in 19% of patients who had cardiac arrest with a nonshockable rhythm (asystole or pulseless electrical activity), and the use of hypothermia subsequently decreased in this situation. the study by Paul young et al showed the dramatic change in practices in ANZ post TTM […]

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  • 943

Featured

Augmented Renal Clearance in ICU

Dr Swapnil Pawar October 5, 2019

Dr Swapnil Pawar & Dr Jose Chacko What is ARC? Augmented renal clearance (ARC) is the phenomenon of enhanced renal function in critically ill patients. ARC is characterized by a higher than predicted increase in the renal elimination of solutes. It occurs due to an increase in glomerular filtration and altered renal tubular function, usually manifest as an increase in the creatinine clearance. ARC leads to increased clearance of drugs excreted through the kidneys resulting in suboptimal concentrations of important medications, including antibiotics, and may lead to treatment failure. This phenomenon was first described more than 40 years ago in […]

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  • 318

Featured

ICU Journal Club- COACT Trial

Dr Swapnil Pawar September 29, 2019

Dr Swapnil Pawar & Dr Jose Chacko Coronary Angiography after Cardiac Arrest without ST-Segment Elevation Lemkes et al https://www.nejm.org/doi/10.1056/NEJMoa1816897 Background – Out-of-hospital cardiac arrest is a leading cause of death.  A recent study reported a mortality of approximately 40% among patients who had been successfully resuscitated after out-of-hospital cardiac arrest associated with ventricular fibrillation or pulseless ventricular tachycardia.  The most frequent cause of cardiac arrest is ischemic heart disease, and coronary artery disease has been reported in up to 70% of patients who have been resuscitated and are referred for immediate coronary angiography.  However, the cause of arrest is often unclear immediately after the event, and the lack of […]

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  • 593

Gastrointestinal

Nutrition in Acute Pancreatitis

Dr Swapnil Pawar September 23, 2019

by Dr Jose Chacko & Dr Swapnil Pawar Acute pancreatitis is the leading cause of acute hospital admission for gastrointestinal disorders in many countries, and its incidence continues to rise worldwide. The annual incidence of AP ranges from 13 to 45 cases per 100,000 population with the global estimate of 33.74 cases per 100,000 population, causing uneven burden across the globe. The health-care cost in the United States is reported to be $2.5 billion. The overall mortality ranges from 5 to 20% depending on severity. In patients who develop severe necrotizing pancreatitis, mortality is approximately 15%. In cases of infection […]

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  • 656

Podcasting

ICU Journal Club – SBT T-piece Vs PSV

Dr Swapnil Pawar September 15, 2019

by Dr Swapnil Pawar & Dr Jose Chacko Effect of Pressure Support vs T-Piece Ventilation Strategies During Spontaneous Breathing Trials on Successful Extubation Among Patients Receiving Mechanical Ventilation A Randomized Clinical Trial Background – The latest American Thoracic Society guidelines for weaning recommend PSV SBTs with moderate-quality evidence. Among patients receiving mechanical ventilation, readiness for extubation and liberation from ventilatory support is evaluated with a spontaneous breathing trial (SBT). Daily screening of respiratory function by SBT is associated with a shorter duration of mechanical ventilation. After a successful SBT and extubation, 10% to 25% of patients require reintubation, and reintubation […]

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  • 376

Pharmacology

ICU Journal Club – VICCSS Study

Dr Swapnil Pawar September 1, 2019

Dr Swapnil Pawar & Dr Jose Chacko A Pilot, Randomised, Double-Blind Study of Vitamin C in the treatment of Vasoplegic Shock after Cardiac Surgery https://doi.org/10.1053/j.jvca.2019.08.034 Background-  High dose vitamin C has a strong biological rationale in post-cardiac surgery vasoplegia. Vitamin C scavenges reactive oxygen species, which likely contribute to vasoplegia after cardiac surgery, stimulates norepinephrine synthesis, decreases the incidence of atrial fibrillation, cardiac enzyme release, and the level of markers of oxidative stress.  In addition, cardiac surgery patients have decreased vitamin C levels compared to preoperative values suggesting increased consumption and/or dilution. What’s Known-  high dose intravenous vitamin C has […]

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  • 299

Opinion

Critical Care Pattern 4 – Tracheostomy

Dr Swapnil Pawar July 28, 2019

Although increasingly less frequent, placement of a tracheostomy has become a viable alternative to prolonged endotracheal intubation, with the benefits of improving patient comfort, reducing need for sedation, lowering airway resistance, and allowing for easier airway care. There has been considerable debate on the technique, timing and selection of ICU patients. In this review, I cover what’s the current consensus and share my preferred approach.

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  • 41

Opinion

Critical Care Pattern 3- ARDS

Dr Swapnil Pawar July 14, 2019

ARDS is a syndrome and our current approach of “one size fits all” is probably not the right approach to deal with this beast. In this doodly, I managed to summarise my evidence based approach in a graphical way. We need to be cautious while interpreting the evidence and should not jump to the conclusion about certain interventions such as recruitment.

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  • 48

Opinion

Critical Care Patterns

Dr Swapnil Pawar June 7, 2019

Critical Care Patterns Intensive care is about recognizing the right pattern and then treating accordingly. It’s similar to game of Chess, where grand masters look at the board, recognize the pattern and make a next move. In this series, I will bring different critical care patterns, which will be helpful to all ICU trainees for their exam preparation and day to day patient management.

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  • 52

Opinion

Networking as a Medical Educator

Dr Swapnil Pawar January 1, 2019

by Swapnil Pawar and Mike Gisondi What is Networking? Networking is the sharing of ideas through a conversation between individuals who have something in common. It’s that simple. The word, ‘networking’, carries a negative connotation, an activity carried out by the ruthless to get ahead. Not true of networking in medical education. The wonderful example of the power of networking in medical education is ALiEM: Academic Life In Emergency Medicine.  ALiEM is a globally distributed digital community of practice hosted as a blog and podcast out of the United States. The organization has grown and enriched over the past 5 […]

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  • 82

Opinion

Acute RV Failure

Dr Swapnil Pawar July 20, 2018

The left ventricle (LV) gets the glory typically. Any echo request usually relates to LV ejection fraction, filing status or regional wall motion abnormality. Perhaps this is fair enough as the LV is a significant contributor to blood flow and organ perfusion, but as Pinsky said at the CICM ASM in Hobart “Right ventricle (RV) function is not considered important for cardiac function until it is … and then it’s everything”. RV dysfunction is rife in the ICU: as a direct result of diseases such as sepsis, and indirectly by mechanical ventilation or pulmonary hypertension, and it is strongly associated […]

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  • 11

Opinion

Post-Cardiac Arrest Management – Time to Say Goodbye to Self Fulfilling Prophesy

Dr Swapnil Pawar July 3, 2018

Robert Rosenthal defined the Pygmalion effect as “the phenomenon whereby one person’s expectation for another person’s behavior comes to serve as a self-fulfilling prophecy” (1) 2015 ILCOR guidelines (2) seem to sway away from self-fulfilling prophesy approach in prognostication post cardiac arrest patients. Successful return of spontaneous circulation (ROSC) is the first step towards the goal of complete recovery from cardiac arrest. The complex pathophysiological processes that occur following whole-body ischemia during cardiac arrest and the subsequent reperfusion response during CPR and following successful resuscitation have been termed the post-cardiac arrest syndrome. The post-cardiac arrest syndrome comprises post-cardiac arrest brain […]

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  • 7

Opinion

Mechanical Chest Compression Devices, are we looking at the new MAST suit?

Dr Swapnil Pawar July 2, 2018

Similarities between the implementation and withdrawal of the military antishock trousers (MAST suit) and the implementation of mechanical chest compression devices are made. The MAST suit has a specific place in the history of prehospital care and emergency care rising in popularity and being withdrawn over a period of approximately 30 years. Both devices demonstrated effectiveness against the surrogate markers of raising blood pressure for the MAST suit and improving perfusion under CPR for the mechanical chest compression devices.  Unfortunately, both have provided disappointing results against the ultimate outcome marker of survival. The possibility that the chest compression devices will […]

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  • 7

Opinion

HepatoRenal Syndrome- Contain the Beast, if You Can

Dr Swapnil Pawar May 8, 2018

Introduction Hepato-renal syndrome is a major complication of decompensated cirrhosis, entailing significant morbidity and mortality in the absence of liver transplant. It still remains a clinical diagnosis of exclusion due to lack of specific diagnostic markers. It is classified as either rapidly developing acute kidney injury (AKI) HRS type 1 or slowly developing chronic kidney disease (CKD) type 2. Both types of HRS are associated with significant decrease in renal blood flow and GFR. The median survival after diagnosis is roughly 1 month for HRS type 1 and 6.7 months for HRS type 2.(1) History and Pathophysiology The association of […]

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  • 4

Opinion

Negotiation in Health Care- Opportunity Not Obstacle

Dr Swapnil Pawar September 30, 2017

In life you don’t get what you deserve, you get what you negotiate for, says Ziad Abdelnour.A day doesn’t do by where we don’t negotiate. We negotiate with our partner/spouse, kids & sometimes even with your self. In hospital settings, we negotiate with an organisation for better work-life balance, we negotiate with colleagues for swapping shifts and we negotiate with families over treatment limitations. However, often our notion is “negotiations are tough and need special skills”. Thus we try to avoid them. One of the reasons for this apathy is lack of training and lack of understanding of principles. What […]

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  • 29

Opinion

All Bleeding Stops Eventually

Dr Swapnil Pawar July 10, 2017

Treating hypovolemic shock secondary to haemorrhage seems very simple. Replace blood for blood. As I grew in my career, I realised that this is far more complex than I thought. James Blundell was the first to notice the importance of blood transfusion, as he observed many females were dying in postpartum period due to PPH. In 1829, he invented first blood transfusion set and saved lives of many. Thereafter, transfusion medicine has evolved rapidly. Why bother? The most dangerous complication of massive transfusion is DEATH. This is attributed to well-known TRIAD of Death, which comprised of Hypothermia, Acidosis & Coagulopathy. […]

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